Nuclear magnetic resonance (NMR)
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- NMR spectroscopy (400-800 MHz) to study samples in solution and observe active nuclei (1H, 13C, 19F, 31P, 113Cd, 195Pt, 29Si, 15N, etc.).
- Structural determination of organic and inorganic compounds (small-medium molecular weight).
- One- and two-dimensional experiments (COSY, DQF, COSY, TOCSY, HSQC, HMBC, NOESY). Difussion experiments DOSY.
- Combined experiments such as HMQC-TOCSY and other heteronuclear experiments.
- Analysis of complex structures (natural products, compounds of biological interest)
- Multi-dimensional experiments for structural determination in proteins.
- Combined use of 1H, 13C and 15N for the study of complex molecules such as proteins through 2 and 3D inverse detection experiments.
- Implementation of new sequences and methods; methodological development and application.
- Control of synthesis processes and/or purification of organic compounds
- Determination of impurities and minority components; quantitative analyses.
- DOSY diffusion experiment
- Process monitoring, kinetic monitoring; variable temperature experiments.
- Determination of interactions between proteins and low-molecular weight compounds.
- Work conducted in accordance with standardized procedures (SOP) for the analysis of APIs (USP, European Pharmacopoeia and ASTM standards). DOSY diffusion experiments.
- Identification of compounds, spectral assignment, reports and evaluations.
- NMR spectral assignment for the identification of structures.
- Heparin analysis (in compliance with FDA-USP and European and Japanese Pharmacopoeia standards).
- Polaxamer analysis (according to EP, USP procedure).
- PGLA polymer analysis (in accordance with ASTM standards).
- Identification analysis for compliance with REACH standard.
- Study of metabolites resulting from the application of an active ingredient (whether directly or through a prior HPLC system treatment).
- Quantitative analysis through the use of internal patterns.
- Determination of the degree of deuteration.
- Study of purity and soluble polymers composition
- Application of NMR in the analysis of food products (oils, dairy, juices, additives, etc.).
- Consulting and training for the optimization of the use of existing NMR instrumentation at private centers.
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Surname
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Name
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Location
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Phone number
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Email
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CARDENAS LOPEZ
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FRANCISCO (*)
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Fac. Química C/ Martí i Franquès, 1
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934021324/
934021328
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fran@ccit.ub.edu
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GAIRI TAHULL
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MARGARIDA
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Edifici Clúster (PCB) C/ Baldiri Reixac, 10
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934034466
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marga@ccit.ub.edu
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GALLEN ORTIZ
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ALBERT
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Fac. Farmàcia Av.Joan XXIII s/n
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934021891
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agallen@ccit.ub.edu
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GONZALEZ GONZALEZ
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MAITE
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Fac. Química C/ Martí i Franquès, 1
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934021324/
934021328
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tgonzalez@ccit.ub.edu
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MERIEL MARCO
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VÍCTOR
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Fac. Química C/ Martí i Franquès, 1
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934021324
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vmeriel@ccit.ub.edu
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MOLINS MONTSERRAT
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Mª ANTONIA
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Edifici Clúster (PCB) C/ Baldiri Reixac, 10
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934021324
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molins@ccit.ub.edu
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MUÑOZ-TORRERO LOPEZ-IBARRA
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VICTORIA
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Edifici Clúster (PCB) C/ Baldiri Reixac, 10
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934034466
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vmunoztorrero@ccit.ub.edu
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NIETO FERNANDEZ
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OSCAR
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Edifici Clúster (PCB) C/ Baldiri Reixac, 10
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934034466
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oscarnieto@ccit.ub.edu
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PUIG MIELGO
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DANIEL
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Fac. Química C/ Martí i Franquès, 1
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934021324
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danielpuig@ccit.ub.edu
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(*) for more information
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