Nuclear magnetic resonance (NMR)

Contact: informn@ccit.ub.edu

	NMR spectroscopy (400-800 MHz) to study samples in solution and observe active nuclei (1H, 13C, 19F, 31P, 113Cd, 195Pt, 29Si, 15N, etc.).
	HR-MAS: NMR spectroscopy to study samples in gel and tissues. Hyperpolarization system.

	Structural determination of organic and inorganic compounds (small-medium molecular weight).
	One- and two-dimensional experiments (COSY, DQF, COSY, TOCSY, HSQC, HMBC, NOESY). Difussion experiments DOSY.
	Combined experiments such as HMQC-TOCSY and other heteronuclear experiments.
	Analysis of complex structures (natural products, compounds of biological interest) Multi-dimensional experiments for structural determination in proteins.
	Combined use of 1H, 13C and 15N for the study of complex molecules such as proteins through 2 and 3D inverse detection experiments.
	Implementation of new sequences and methods; methodological development and application.
	Control of synthesis processes and/or purification of organic compounds Determination of impurities and minority components; quantitative analyses.
	HR-MAS experiments for samples in gel or semi-solids; study of metabolites in tissues.
	Process monitoring, kinetic monitoring; variable temperature experiments.
	Determination of interactions between proteins and low-molecular weight compounds.
	Work conducted in accordance with standardized procedures (SOP) for the analysis of APIs (USP, European Pharmacopoeia and ASTM standards). DOSY diffusion experiments.
	Identification of compounds, spectral assignment, reports and evaluations.

	NMR spectral assignment for the identification of structures.
	Heparin analysis (in compliance with FDA-USP and European Pharmacopoeia standards).
	Poloxamer analysis (according to USP procedure).
	PGLA polymer analysis (in accordance with ASTM standards).
	Identification analysis for compliance with REACH standard.
	Study of metabolites resulting from the application of an active ingredient (whether directly or through a prior HPLC system treatment).
	Quantitative analysis through the use of internal patterns.
	Determination of the degree of deuteration.
	Purity studies and studies of the composition of soluble polymers. HR-MAS experiments with tissues.
	Application of NMR in the analysis of food products (oils, dairy, juices, additives, etc.).
	Consulting and training for the optimization of the use of existing NMR instrumentation at private centers.

Surname	Name	Location	Phone number	Fax	Email
CARDENAS LOPEZ	FRANCISCO	Fac. Química C/ Martí i Franquès, 1	934021324/ 934021328	934021330	fran@ccit.ub.edu
FELIZ RODENAS (*)	MIQUEL	Edifici Clúster (PCB) C/ Baldiri Reixac, 10	934034466/ 934034464	934034465	mfeliz@ccit.ub.edu
GAIRI TAHULL	MARGARIDA	Edifici Clúster (PCB) C/ Baldiri Reixac, 10	934034466	934034465	marga@ccit.ub.edu
GONZALEZ GONZALEZ	MAITE	Fac. Química C/ Martí i Franquès, 1	934021324/ 934021328	934021330	tgonzalez@ccit.ub.edu
LINARES OBON	ANA MARIA	Fac. Farmàcia Av.Joan XXIII s/n	934021891	934021398	alinares@ccit.ub.edu
MERIEL MARCO	VICTOR	Fac. Química C/ Martí i Franquès, 1	934021324	934021330	vmeriel@ccit.ub.edu
MOLINS MONTSERRAT	Mª ANTONIA	Edifici Clúster (PCB) C/ Baldiri Reixac, 10	934034466/ 934034463	934034465	molins@ccit.ub.edu
MUÑOZ-TORRERO LOPEZ-IBARRA	VICTORIA	Edifici Clúster (PCB) C/ Baldiri Reixac, 10	934034466	934034465	vmunoztorrero@ccit.ub.edu
NIETO FERNANDEZ	OSCAR	Edifici Clúster (PCB) C/ Baldiri Reixac, 10	934034466	934034465	oscarnieto@ccit.ub.edu
PELEGRI MARGELI	EVA	Edifici Clúster (PCB) C/ Baldiri Reixac, 10	934034466	934034465	evap@ccit.ub.edu

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