Centres Científics i Tecnològics UB



New 400Mhz NMR equipment at CCiTUB

The installation of a new Nuclear Magnetic Resonance Equipment was completed on March 31, 2022. This equipment is a 400 MHz Bruker Advance Neo, and has been installed in the NMR laboratory of the Scientific and Technological Centers located in the Faculty of Pharmacy of the University of Barcelona.

The acquisition of this NMR spectrometer has been carried out through the granting, in 2019, of FEDER funds for the co-financing of the team within the “Subprograma Estatal De Infraestructuras De Investigación Y Equipamiento Científico Técnico, En El Marco Del Plan Estatal De Investigación Científica Y Técnica Y De Innovación 2017-2020”


The RMN equipment contains a double-shielded 9.39 Tesla (400 MHz) superconducting magnet with an independent two-channel console capable of observing, pressing and uncoupling with a temporary resolution of 12.5 ns. The equipment contains two linear amplifiers of 100 W and 50 W for 1H and 13C, respectively. The spectrometer works with a high-sensitivity Prodigy chrysos probe cooled by liquid nitrogen with a sensitivity 2 to 3 times higher than conventional probes (SN 1050:1 in 1H, 475:1 in 13C). In addition, the cryoprobe allows self-tuning to detect nuclei 19F, 31P, 11B, 29Si, among others.

The spectrometer incorporates a gradient system with 36 coils for optimal adjustment of homogeneity and line shape. The team can also perform NMR spectra at varying temperatures (-40 ° to + 150 ° C). The high work capacity of the equipment should be highlighted thanks to the incorporation of a 60-sample automatic changer that will allow a large number of daily NMR spectra to be obtained.

The spectrometer will serve a large number of researchers, mainly from the UB, in the field of Organic, Inorganic and Pharmaceutical Chemistry. In these fields of knowledge, NMR is becoming key as a tool for the rapid identification and verification of new medium-sized molecules of great therapeutic interest. It will also serve other emerging research groups in areas such as bio-organic, bio-inorganic, new materials and biotechnology.