Centres Científics i Tecnològics UB

Notícies

19.04.2018

Publicació de l'article “Assembling the Puzzle of Apixaban Solid Forms”

El Dr. Rafel Prohens, Responsable de la tecnologia de Polimorfisme i Calorimetria dels CCiTUB, juntament amb el Dr. Rafael Barbas i la Dra. Cristina Puigjaner, tècnics de la mateixa tecnologia, han publicat l'article: “Assembling the Puzzle of Apixaban Solid Forms” a la revista Molecular Pharmaceutics publicada el passat dia 27 de Març.

El resum de l'article és el següent:

"An in-depth analysis of the solid forms of the anticoagulant drug Apixaban (APX) has been conducted to sort out the confusion in the scientific and patent literature regarding the solid forms landscape. The nomenclature employed and the accompanying characterization data are often unclear and incomplete, leading to a situation in which apparently the same form has been reported by different authors or claimed by different inventors. A comprehensive solid forms screen and a full and careful comparison with the literature data has been performed to draw a reliable picture of the solid forms landscape of APX."

Per a més informació, poden accedir al següent link:[+].