Centres Científics i Tecnològics UB

News

19.04.2018

Publication of the article “Assembling the Puzzle of Apixaban Solid Forms”

PhD. Rafel Prohens, Responsible of the Polymorphism and Calorimetry Technology of the CCiTUB, along with PhD. Rafael Barbas and PhD. Cristina Puigjaner, technicians of the same technology, have published the article: “Assembling the Puzzle of Apixaban Solid Forms” in the journal Molecular Pharmaceutics published on March 27th.

The summary of the article is:

"An in-depth analysis of the solid forms of the anticoagulant drug Apixaban (APX) has been conducted to sort out the confusion in the scientific and patent literature regarding the solid forms landscape. The nomenclature employed and the accompanying characterization data are often unclear and incomplete, leading to a situation in which apparently the same form has been reported by different authors or claimed by different inventors. A comprehensive solid forms screen and a full and careful comparison with the literature data has been performed to draw a reliable picture of the solid forms landscape of APX."

More information about the article in question is available at the following link:[+].