Centres Científics i Tecnològics UB

News

16.03.2021

Publication of the paper "A New and Highly Stable Cocrystal of Vitamin D3 for Use in Enhanced Food Supplements"

PhD. Rafel Prohens, responsible of the Polymorphism and Calorimetry Unit of the CCiTUB, along with PhD. Rafael Barbas and Mrs. Dafne de Sande of the same technology, and Mrs Lídia Bofill from CIRCE (Center for Intelligent Research in Crystal Engineering S.L), have published the paper "A New and Highly Stable Cocrystal of Vitamin D3 for Use in Enhanced Food Supplements" in the Crystal Growth & Design journal. The paper is a result of an agreement between CCiTUB and the company CIRCE.

The Crystal Growth & Design journal belongs to the American Chemical Society and is scientific journal of biggest impact in the Crystal Engineering (Q1, IF= 4.1), field of work of Unit.

The summary of the article is:

"A new cocrystal of Vitamin D3 (Cholecalciferol) and resorcinol has been discovered and characterized through experimental cocrystal screening. Its high stability has been studied against light, heat, and chemicals present in animal food premixes in order to develop a novel and alternative formulation to current microencapsulation approaches to protect Vitamin D3 from oxidation. Our results show that the new cocrystal is extremely stable and it can become the basis for very efficient formulations of Vitamin D3 which fulfills the stability requirements of industrial applications."