News17.01.2018Prize to a doctoral thesis directed by a technician of the CCiTUB |
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Last Friday December 15 was held at the headquarters of the Institut d'Estudis Catalans the award ceremony of the CCNIEC-EROSKI awards granted by the Catalan Center for Nutrition of the Institute of Catalan Studies to the best doctoral theses on nutrition and food. These awards were given to the students Violeta Moizé and Paola Quifer. One of the winning doctoral theses, written by the student Paola Quifer and entitled “Risk and benefits of beer and nonalcoholic beer moderate on cardiovascular system”, was co-directed by PhD. Olga Jáuregui, technician of the Separative techniques technology of the CCiTUB. The abstract of the thesis is as follows: “Beer is by far the most widely consumed alcoholic beverage in the world. Moderate alcohol consumption in general has been inversely associated with incident cardiovascular disease in observational studies. However, it has been suggested that fermented beverages such as red wine and beer may confer greater protective effects than spirits owing to their higher polyphenolic content. Polyphenols are secondary plant metabolites that are not essential for short-term health status, however there is increasing evidence that long-term intake may reduce the incidence of chronic diseases such as cancer, type-II diabetes, cardiovascular diseases and neurodegenerative diseases. Beer phenolic profile is very diverse, most of the beer polyphenols come from malt, and the rest come from hops used during brewing. However, although hop polyphenols in beer are found in low concentrations, they are very specific to beer since they are not detected in other foods. Most techniques used in assessing the diet followed by individuals are based on self-reporting questionnaires, which are liable to systematic bias by factors such as age, gender, social desirability and approval. In this thesis, we aim to evaluate whether regular and moderate beer and non-alcoholic beer consumption may reduce cardiovascular disease risk. To assess beer intake one of the main objectives of this thesis was to find a reliable biomarkers of beer consumption, and for this purpose we developed and validated a new method to determine hops polyphenols (prenylflavonoids). We evaluated the effects of ethanol and the phenolic compounds of beer on classical and novel cardiovascular risk factors with an interventional nutritional trial with participants at high cardiovascular risk. Moreover, in a large, multicenter, randomized, parallel group we performed a prospective study aimed at assess the differential associations of wine, beer and spirit consumption with all-cause mortality and incidence of cardiovascular events.” |
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